南方科技大学是由中国广东省领导和管理、深圳市举全市之力创建的一所公办创新型大学,目标是迅速建成国际化高水平研究型大学,建成中国重大科学技术研究与拔尖创新人才培养的重要基地……

南方科技大学以学分制、导师制、书院制为基础,以人才培养的个性化、小班化、国际化为特色,通过为一流的人才培养体系,培养人格健全、基础扎实、能力突出、具有国际视野、社会责任感、创新精神和实践能力的高素质人才。

南方科技大学被确定为国家高等教育综合改革试验校。2012年4月,教育部同意建校,并赋予学校探索具有中国特色的现代大学制度、探索创新人才培养模式的重大使命。

南方科技大学对本科学生采用书院制管理模式,以书院、团委、社团等平台为载体,为学生营造了精彩的大学生活。

南方科技大学本科招生采用基于高考的综合评价录取模式,即高考成绩占60%,我校自主组织的能力测试成绩占30%(其中面谈成绩为5%),高中学业水平考试成绩占10%,按考生“631”综合成绩排名从高到低录取。综合评价录取模式由我校在2012年率先实施。

南科大教育基金会由理事会、监事会、秘书处组成。理事会是基金会的最高权力机构;监事会负责检查财务和会计资料,监督理事会遵守法律和章程的情况;秘书处是基金会常设办事机构,在理事会领导下负责基金会的日常工作。

学校党委切实履行党建工作职责,不断强化班子建设和基层党组织建设,充分发挥好党委对学校各项工作的核心统领作用和各党支部的战斗堡垒作用,切实开展组织统战和党风廉政建设各项工作。学校高度重视群团组织建设,充分调动全体师生员工积极性,维护教职工的合法权益,推进学校民主管理,促进学校健康发展,全力营造齐心协力、团结向上、奋发有为的干事创业氛围。

导师简介

首页 > 学生生活 > 树礼书院 > 导师简介 > Peter Pimpl

师资队伍

Peter Pimpl


助理教授

生物系

0755-88018485

pimpl@sustc.edu.cn

Self-introduction:

Research in my group is centered on the molecular characterization of protein sorting and transport processes in the plant endomembrane system. In particular focus are: receptor-mediated sorting of soluble proteins, degradation of membrane proteins and biogenesis of intracellular compartments. Our research aims at exploiting cells to synthesize bioactive molecules. We explore strategies to implement artificial sorting receptors, to engineer vesicular transport processes and aim at the generation of novel functionalized compartments. For this, we combine molecular biology and biochemistry with light and electron microscopy and pioneer the use of nanobody fusion proteins for the non-invasive analysis and manipulation of cellular functions.

 

Research Interests: 
◆ Receptor-mediated sorting of proteins
◆ Vesicle-mediated transport processes
◆ Biogenesis and aging of intracellular compartments

 

Professional Experience:
◆ Associate Professor, SUSTech-PKU Institute of Plant and Food Science (IPF), Department of Biology, Southern University of Science and Technology, Shenzhen, China, 2017-present
◆ Independent Research Group Leader, Center for Plant Molecular Biology (ZMBP), Eberhard Karls University Tuebingen, Germany, 2009-2017
◆ Research Group Leader, Heidelberger Institute for Plant Sciences (HIP), Ruprecht-Karls University Heidelberg, Germany, 2005-2009
◆ Postdoc researcher at the Center for Plant Sciences, University of Leeds, United Kingdom, 2003-2005
◆ Marie Curie postdoctoral research fellow at the Center for Plant Sciences, University of Leeds, United Kingdom, 2001-2003
◆ Research Assistant, Albrecht-von-Haller Institute for Plant Sciences, Georg August University Goettingen, Germany, 1999-2000

 

Educational Background:
◆ Dr. rerum naturalis / Ph.D. degree in Sciences, awarded summa cum laude, Georg August University Goettingen, Germany, 2001-05-03
◆ Diploma in Biology, subjects: Botany, Microbiology and Chemistry, Georg August University Goettingen, Germany, 1997-11-03

 

Honors & Awards:
◆ “Horst-Wiehe-Prize” of the German Society for Plant Sciences (DBG) for outstanding scientific work in the field of Botany. Freiburg, Germany, 2002
◆ Marie Curie Individual post-doctoral Fellowship of the European Union (EU), 2001

 

Selected Publication: 
◆ Künzl, F., Früholz, S., Fäßler, F. Li, B. and Pimpl, P.* (2016) Receptor-mediated sorting of soluble vacuolar proteins ends at the trans-Golgi network/early endosome (TGN/EE). Nature Plants 2, Article number 16017
*corresponding author
◆ Robinson, D.G. and Pimpl, P.* (2014). Receptor-mediated transport of vacuolar proteins: a critical analysis and a new model. Protoplasma 251, 247-264.
*corresponding author
◆ Robinson, D.G., and Pimpl, P. (2014). Clathrin and post-Golgi trafficking: a very complicated issue. Trends Plant Sciences 19, 134-139.
◆ Shen, J., Zeng, Y., Zhuang, X., Sun, L., Yao, X., Pimpl, P., and Jiang, L. (2013). Organelle pH in the Arabidopsis Endomembrane System. Molecular Plant 6, 1419-1437.
◆ Scheuring, D., Künzl, F., Viotti, C., San Wan Yan, M., Jiang, L., Schellmann, S., Robinson, D.G., and Pimpl, P.* (2012). Ubiquitin initiates sorting of Golgi and PM proteins into the vacuolar degradation pathway. BMC Plant Biology 12, 164.
*corresponding author
◆ Robinson, D.G., Pimpl, P., Scheuring, D., Stierhof, Y.D., Sturm, S., and Viotti, C. (2012). Trying to make sense of retromer. Trends Plant Sciences 17, 431-439.
◆ Cai, Y., Jia, T., Lam, S.K., Ding, Y., Gao, C., San, M.W., Pimpl, P., and Jiang, L. (2011). Multiple cytosolic and transmembrane determinants are required for the trafficking of SCAMP1 via an ER-Golgi-TGN-PM pathway. Plant Journal 65, 882-896.
◆ Scheuring, D., Viotti, C., Kruger, F., Künzl, F., Sturm, S., Bubeck, J., Hillmer, S., Frigerio, L., Robinson, D.G., Pimpl, P.*, and Schumacher, K. (2011). Multivesicular bodies mature from the trans-Golgi network/early endosome (TGN/EE) in Arabidopsis. Plant Cell 23, 3463-3481.
*corresponding author
◆ Niemes, S., Labs, M., Scheuring, D., Krueger, F., Langhans, M., Jesenofsky, B., Robinson, D.G., and Pimpl, P.* (2010). Sorting of plant vacuolar proteins is initiated in the ER. Plant Journal 62, 601-614.
*corresponding author
◆ Niemes, S., Langhans, M., Viotti, C., Scheuring, D., Yan, M.S., Jiang, L., Hillmer, S., Robinson, D.G., and Pimpl, P.* (2010). Retromer recycles vacuolar sorting receptors from the trans-Golgi network. Plant Journal 61, 107-121.
*corresponding author
◆ Shahriari, M., Keshavaiah, C., Scheuring, D., Sabovljevic, A., Pimpl, P., Häusler, R.E., Hülskamp, M., and Schellmann, S. (2010). The AAA-type ATPase AtSKD1 contributes to vacuolar maintenance of Arabidopsis thaliana. Plant Journal 64, 71-85.
◆ Lam, S. K., Cai, Y., Tse, Y. C. Wang, J., Pimpl, P., Chan, H. Y. E., Xia, J. and Jiang, L (2009) The BFA-induced compartments from Golgi apparatus and trans-Golgi network are morphologically and functionally distinct in plant cells. Plant Journal 60, 865-881.

◆ Schellmann, S*. and Pimpl, P.* (2009). Coats of endosomal protein sorting: retromer and ESCRT. Current Opinion Plant Biology 12, 670-676.
*corresponding author
◆ Langhans, M., Niemes, S., Pimpl, P. and Robinson, D. G. (2009) Oryzalin bodies: In addition to its antimicrotubule properties the dinitroaniline herbicide oryzalin causes nodulation of the endoplasmic reticulum. Protoplasma 236, 73-84.
◆ Langhans, M., Marcote, M.J., Pimpl, P., Virgili-Lopez, G., Robinson, D.G., and Aniento, F. (2008). In vivo Trafficking and Localization of p24 Proteins in Plant Cells. Traffic 9, 770-785.
◆ Pimpl, P., Taylor, J.P., Snowden, C., Hillmer, S., Robinson, D.G and Denecke, J. (2006) Golgi-mediated vacuolar sorting of the endoplasmic reticulum chaperone BiP may play an active role in quality control within the secretory pathway. Plant Cell 18, 198-211.
◆ Pimpl, P., Hanton, S. L., Taylor, J. P., Pinto-DaSilva, L. L., and Denecke, J. (2003). The GTPase ARF1p Controls the Sequence-Specific Vacuolar Sorting Route to the Lytic Vacuole. Plant Cell 15, 1242-1256.
◆ Ritzenthaler, C., Nebenführ, A., Movafeghi, A., Stussi-Garaud, C., Behnia, L., Pimpl. P., Staehelin, L.A., Robinson, D.G (2002) Reevaluation of the effects of brefeldin A on plant cells using tobacco BY-2 cells expressing Golgi-targeted GFP and COPI-antisera. Plant Cell 14, 237-261.
◆ Pimpl, P. and Denecke, J. (2002) Protein interactions in the secretory pathway, a growing demand for experimental approaches in vivo. Plant Molecular Biology 50, 887-902.
◆ Phillipson, B.A*., Pimpl, P.*, Lamberti Pinto daSilva, L., Crofts, A.J., Taylor, J.P., Movafeghi, A., Robinson, D.G., Denecke, J. (2001) Secretory bulk flow of soluble proteins is efficient and COPII dependent. Plant Cell 13, 2005-2020. 
* contributed equally, listed alphabetically 
◆ Törmäkangas, K., Hadlington, J.L., Pimpl, P., Hillmer, S., Brandizzi, F., Teeri, T.H. Denecke, J. (2001) A vacuolar sorting domain may also influence the way in which proteins leave the endoplasmic reticulum. Plant Cell 13, 2021-2032.
◆ Pimpl, P., Movafeghi, A., Coughlan, S., Denecke, J., Hillmer, S., Robinson, D.G. (2000) In situ localization and in vitro induction of plant COPI-coated vesicles. Plant Cell 12, 2219-2235.
◆ Pimpl, P. and Denecke, J. (2000) ER retention of soluble proteins: Retrieval, retention, or both? Plant Cell 12, 1517-1519.
◆ Movafeghi, A., Happel, N., Pimpl, P., Tai, G-H., and Robinson, D.G. (1999) Arabidopsis Sec21p and Sec23p homologs. Probable coat proteins of plant COP-coated vesicles. Plant Physiology 119, 1437-1445.

 

Other Info:
◆ The research group has current vacancies ranging from internships and jobs for working students through to jobs for postdoctoral researchers. We also offer topics for bachelor or master theses. Please feel free to contact us.

研究方向

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