南方科技大学是由中国广东省领导和管理、深圳市举全市之力创建的一所公办创新型大学,目标是迅速建成国际化高水平研究型大学,建成中国重大科学技术研究与拔尖创新人才培养的重要基地……

南方科技大学以学分制、导师制、书院制为基础,以人才培养的个性化、小班化、国际化为特色,通过为一流的人才培养体系,培养人格健全、基础扎实、能力突出、具有国际视野、社会责任感、创新精神和实践能力的高素质人才。

南方科技大学被确定为国家高等教育综合改革试验校。2012年4月,教育部同意建校,并赋予学校探索具有中国特色的现代大学制度、探索创新人才培养模式的重大使命。

南方科技大学对本科学生采用书院制管理模式,以书院、团委、社团等平台为载体,为学生营造了精彩的大学生活。

南方科技大学本科招生采用基于高考的综合评价录取模式,即高考成绩占60%,我校自主组织的能力测试成绩占30%(其中面谈成绩为5%),高中学业水平考试成绩占10%,按考生“631”综合成绩排名从高到低录取。综合评价录取模式由我校在2012年率先实施。

南科大教育基金会由理事会、监事会、秘书处组成。理事会是基金会的最高权力机构;监事会负责检查财务和会计资料,监督理事会遵守法律和章程的情况;秘书处是基金会常设办事机构,在理事会领导下负责基金会的日常工作。

学校党委切实履行党建工作职责,不断强化班子建设和基层党组织建设,充分发挥好党委对学校各项工作的核心统领作用和各党支部的战斗堡垒作用,切实开展组织统战和党风廉政建设各项工作。学校高度重视群团组织建设,充分调动全体师生员工积极性,维护教职工的合法权益,推进学校民主管理,促进学校健康发展,全力营造齐心协力、团结向上、奋发有为的干事创业氛围。

书院导师

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师资队伍

刘心元


副教授

化学系

0755-88018314

liuxy@sustc.edu.cn


    2001年在安徽师范大学化学系获学士学位,2004年在中国科学院上海有机化学研究所获硕士学位,师从王绍武教授和朱仕正研究员;2010年在香港大学获哲学博士学位,师从支志明院士。2010年4月至2012年9月先后在香港大学和美国The Scripps Research Institute从事博士后研究。2012年9月加入南方科技大学化学系。现为广东省化学会“有机化学专业委员会委员”。曾获得香港大学2009-2010年杰出研究生奖,入选深圳市海外高层次“孔雀计划”B类人才等。研究方向是围绕非活性烯烃和炔烃的不对称官能团化开展工作。已在国内外期刊上共发表SCI检索论文46篇,其中以第一作者或通讯作者发表的论文期刊34篇如Angew. Chem. Int. Ed.(9篇)、ACS Catal.(1篇), Chem. Commun.(3篇)、Org. Lett.(8篇)及 Chem. Eur. J.(3篇)等;其中7篇论文被Synfacts亮点评述(Synfacts 2014, 10, 1281; 2014, 10, 1272; 2014, 10, 754; 2014, 10, 530; 2013, 9, 1251; 2009, 5, 600; 2009, 5, 1363.);4篇论文被选为封面和插图文章;2篇论文被选为热点文章;1篇论文被Organic Chemistry Portal(有机化学门户)亮点报道;1篇Org. Lett.论文在2009年被选为该杂志三年内发表的引用次数最多的20篇文章之一。引用次数达1266次;其中有三篇论文单篇引用次数达119次。
  2012年底在南方科技大学开展独立的科研工作,迅速建立科研团队。目前主要围绕均相和非均相(金属框架)催化剂的设计与他们组成协同催化剂参与的非活性烯烃和炔烃不对称官能团化及不对称氟化学反应的应用。在短短两年时间里积累了丰富的研究经验并取得了多项创新性成果,以通讯作者身份在高影响力期刊上发表20篇具有重要学术影响力的论文,如Angew. Chem. Int. Ed.(6), ACS Catal.(1), Chem. Commun.(3), Org. Lett.(4), Chem. Eur. J.(2)等。其中五篇论文分别被Synfacts专题评述 (Synfacts 2014, 10, 1281; 2014, 10, 1272; 2014, 10, 754; 2014, 10, 530; 2013, 9, 1251.)。最近发表的论文Angew. Chem. Int. Ed. (2015, 54, 4041.)被选为该杂志的封面文章;同时,2013年发表的论文Chem. Commun. (2013, 49, 7681.)被选为该杂志的封面文章,同时被选为热点文章。

 

Publications:

 

1. Zhi-Jia Fang, Sheng-Cai Zheng, Zhen Guo, Jing-Yao Guo, Bin Tan,* Xin-Yuan Liu*, Asymmetric Synthesis of Axially Chiral Isoquinolones: Nickel-Catalyzed Denitrogenative Transannulation Angew. Chem. Int. Ed. 2015, 54, DOI: 10.1002/anie. 201503207.
2. Jin-Shun Lin, Peng Yu, Lin Huang, Pan Zhang, Bin Tan,* Xin-Yuan Liu*, Brønsted Acid-Catalyzed Asymmetric Hydroamination of Alkenes: Synthesis of Pyrrolidines Bearing a Tetrasubstituted Carbon Stereocenter Angew. Chem. Int. Ed. 2015, 54, DOI: 10.1002/anie.201501762.
3. Peng Yu, Sheng-Cai Zheng, Ning-Yuan Yang, Bin Tan,* Xin-Yuan Liu*,Phosphine-Catalyzed Remote β-C-H Functionalization of Amine Triggered by Trifluoromethylation of Alkene: One-Pot Synthesis of Bistrifluoromethylated Enamides and Oxazoles, Angew. Chem. Int. Ed. 2015, 54, 4041-4045 (Selected as Cover Picture). 
4. Peng Yu, Jin-Shun Lin, Lei Li, Sheng-Cai Zheng, Ya-Ping Xiong, Li-Jiao Zhao, Bin Tan*, and Xin-Yuan Liu* “Enantioselective C-H Bond Functionalization Triggered by Radical Trifluoromethylation of Unactivated Alkene” Angew. Chem. Int. Ed. 2014, 53, 11890. 
Highlighted in Synfacts, 2014, 10, 1281.
5. Ming-Yue Wu, Wei-Wei He, Xin-Yuan Liu*, Bin Tan,* Asymmetric Construction of Spirooxindoles via Organocatalytic Multicomponent Reactions of Diazooxindoles Angew. Chem. Int. Ed. 2015, 54, DOI: 10.1002/anie. 201504640.
6. Dao-Juan Cheng, Liang Yan, Shi-Kai Tian,* Ming-Yue Wu, Lu-Xin Wang, Zi-Li Fan, Sheng-Cai Zheng, Xin-Yuan Liu,* and Bin Tan* “Highly Enantioselective Kinetic Resolution of Axially Chiral BINAM Derivatives Catalyzed by a Brønsted Acid” Angew. Chem. Int. Ed. 2014, 53, 3684. 
Highlighted in Synfacts, 2014, 10, 530.
7. Lin Huang, Jin-Shun Lin, Bin Tan,* Xin-Yuan Liu*, Alkene Trifluoromethylation-Initiated Remote α-Azidation of Carbonyl Compounds toward Trifluoromethyl γ-Lactam and Spirobenzofuranone-lactam ACS Cat. 2015, 5, 2826-2831.
8. Lin Huang, Sheng-Cai Zheng, Bin Tan,* Xin-Yuan Liu*, Metal-Free Direct 1,6- and 1,2-Difunctionalization Triggered by Radical Trifluoromethylation of Alkenes Org. Lett. 2015, 17, 1589-1592.
9. Lin Huang, Sheng-Cai Zheng, Bin Tan,* Xin-Yuan Liu*, Trifluoromethylation-Initiated Remote Cross-Coupling of Carbonyl Compounds to Form Carbon–Heteroatom/Carbon Bonds Chem. Eur. J. 2015, 21, 6718.
10. Can-Liang Ma, Xiao-Long Yu, Xiao-Long Zhu, Yong-Zhou Hu, Xiao-Wu Dong, Bin Tan*, and Xin-Yuan Liu* “Platinum-Catalyzed Tandem Cyclization Reaction to Multiply Substituted Indolines under Microwave-Assisted Conditions” Adv. Synth. Catal. 2015, 357,569.
11. Lei Li, Jing-Yao Guo, Xing-Guo Liu, Su Chen, Yong Wang, Bin Tan*, and Xin-Yuan Liu* “Amide Groups Switch Selectivity: C-H Trifluoromethylation of α,β-Unsaturated Amides and Subsequent Asymmetric Transformation” Org. Lett., 2014, 16, 6032.
12. Jin-Shun Lin, Xiang-Geng Liu, Xiao-Long Zhu, Bin Tan,* and Xin-Yuan Liu* “Copper-Catalyzed Aminotrifluoromethylation of Unactivated Alkenes with TMSCF3: Construction of Trifluoromethylated Azaheterocycles” J. Org. Chem. 2014, 79, 7084.
13. Xing-Li Zhu, Jin-Hui Xu, Dao-Juan Cheng, Li-Jiao Zhao, Xin-Yuan Liu* and Bin Tan* “In Situ Generation of Electrophilic Trifluoromethylthio Reagents for Enantioselective Trifluoromethylthiolation of Oxindoles” Org. Lett. 2014, 16, 2192.
Highlighted in Synfacts, 2014, 10, 754.
14. Ya-Ping Xiong, Ming-Yue Wu, Xiang-Yu Zhang, Can-Liang Ma, Lin Huang, Li-Jiao Zhao, Bin Tan* and Xin-Yuan Liu* “Direct Access to α-CF3-enones via Efficient Copper-Catalyzed Trifluoromethylation of Meyer-Schuster Rearrangement” Org. Lett. 2014, 16, 1000.
This work is highlighted on the website http:// http://www.organic-chemistry.org/abstracts/lit4/389.shtm
15. Lei Li, Min Deng, Sheng-Cai Zheng, Ya-Ping Xiong, Bin Tan* and Xin-Yuan Liu*. “Metal-Free Direct Intramolecular Carbotrifluoromethylation of Alkenes to Functionalized Trifluoromethyl Azaheterocycles” Org. Lett. 2014, 16, 504.
16. Jin-Shun Lin, Ya-Ping Xiong, Can-Liang Ma, Li-Jiao Zhao, Bin Tan,* and Xin-Yuan Liu*. “Efficient Copper-Catalyzed Direct Intramolecular Aminotrifluoromethylation of Unactivated Alkenes with Diverse Nitrogen-Based Nucleophiles” Chem. Eur. J. 2014, 20, 1332.
17. Tao Liu, Da-Qiang Li, Si-Yu Wang Yong-Zhou Hu, Xiao-Wu Dong,* Xin-Yuan Liu,* and Chi-Ming Che “Straightforward Installation of Carbon-Halogen, Carbon-Oxygen and Carbon-Carbon Bonds within Metal–Organic Frameworks via Direct C-H Functionalization” Chem. Commun., 2014, 50,13261.
   Highlighted in Synfacts, 2014, 10, 1272.
18. Tao Liu, Jin-Xin Che, Yong-Zhou Hu, Xiao-Wu Dong,* Xin-Yuan Liu,* Chi-Ming Che “Alkenyl/thiol-derived Metal–Organic Frameworks via Post-Synthetic Modification for Effective Mercury Adsorption” Chem. Eur. J. 2014, 20,14090.

19. Xiao-Wu Dong, Tao Liu, Yong-Zhou Hu*, Xin-Yuan Liu*, Chi-Ming Che. Urea Postmodified in Metal-Organic Framework as Catalytically Active Hydrogen-Bond-Donating Heterogeneous Catalyst Chem. Commun., 2013, 49, 7681. 
  Highlighted with a front cover in Chem. Commun.; 
  Selected as HOT Chem. Comm. articles for May; 
  Highlighted in Synfacts, 2013, 9, 1251. 

20. Gaosheng Yang,* Chongrong Luo, Xiaolong Mu, Tingting Wang and Xin-Yuan Liu*, Highly efficient enantioselective three-component synthesis of 2-amino-4H-chromenes catalysed by chiral tertiary amine-thioureas Chem. Commun. 2012, 48, 5880-5882.

 

Graduate & Postdoctoral Publications

 

1. Xin-Yuan Liu, Ya-Ping Xiao, Fung-Ming Siu, Li-Chen Ni, Yong Chen, Lin Wang, and Chi-Ming Che*, “Highly regio-, diastereo- and enantioselective one-pot gold/chiral Brønsted acid-catalysed cascade synthesis of bioactive diversely substituted tetrahydroquinolines” Org. Biomol. Chem. 2012, 10, 7208-7219.

2. Xin-Yuan Liu,[+] Zhen Guo,[+] Sijia Dong,[+] Xiao-Hua Li, and Chi-Ming Che*, “Highly efficient and diastereoselective gold(I)-catalyzed synthesis of tertiary amines from secondary amines and alkynes: substrate scope and mechanical insights” Chem. Eur. J. 2011, 17, 12932-12945. [+]denotes equal contribution

3. Ya-Ping Xiao,[+] Xin-Yuan Liu,[+] and Chi-Ming Che*, “Efficient gold(I)-catalyzed direct intramolecular hydroalkylation of unactivated alkenes with simple α-ketones” Angew. Chem. Int. Ed. 2011, 50, 4937-4941. [+]denotes equal contribution

4. Xin-Yuan Liu, Chi-Ming Che*, “Highly enantioselective synthesis of chiral secondary amines by gold(I)/chiral Brønsted acid-catalyzed tandem intermolecular hydroamination and transfer hydrogenation reactions” Org. Lett. 2009, 11, 4204-4207.

5. Xin-Yuan Liu, Chi-Ming Che*, “Highly efficient and regioselective platinum(II)-catalyzed tandem synthesis of multiply substituted indolines and tetrahydroquinolines” Angew. Chem. Int. Ed. 2009, 48, 2367-2371.

6. Xin-Yuan Liu, Chi-Ming Che*, “A highly efficient and selective AuI-catalyzed tandem synthesis of diversely substituted pyrrolo[1,2-α]quinolines in aqueous medium” Angew. Chem. Int. Ed. 2008, 47, 3805-3810.

7. Xin-Yuan Liu, Pan Ding, Jie-Sheng Huang, Chi-Ming Che*, “Synthesis of substituted 1,2-dihydroquinolines and quinolines from aromatic amines and alkynes by gold(I)-catalyzed tandem hydroamination-hydroarylation under microwave-assisted conditions” Org. Lett. 2007, 9, 2645-2648.

8. Xin-Yuan Liu, Cheng-Hui Li, Chi-Ming Che*, “Phosphine gold(I)-catalyzed hydroamination of alkenes under thermal and microwave-assisted conditions” Org. Lett. 2006, 8, 2707-2710. 

9. Xin yuan Liu, Xiaoyu Wu, Zhuo Chai, Yongyong Wu, Gang Zhao*, Shizheng Zhu*, “Highly effective and recyclable dendritic ligands for the enantioselective aryl transfer reactions to aldehydes” J. Org. Chem. 2005, 70, 7432-7435.

 

Selected Works Highlighted by Others or Featured by Journal Editors


1. “Phosphine Gold(I)-Catalyzed Hydroamination of Alkenes under Thermal and Microwave-Assisted Conditions” (X.-Y. Liu, C.-H. Li, C.-M. Che, Org. Lett., 2006, 8, 27072710) is featured on the ACS Publications website as one of “Organic Letters' Hot Papers” based on citation data obtained from Thomson ISI.
2. “Synthesis of Substituted 1,2-Dihydroquinolines and Quinolines from Aromatic Amines and Alkynes by Gold(I)-Catalyzed Tandem Hydroamination-Hydroarylation under Microwave-Assisted Conditions” (X.-Y. Liu, P. Ding, J.-S. Huang, C.-M. Che, Org. Lett., 2007, 9, 26452648) is selected on the ACS Publications website in 2009 as Top 20 most-cited articles published in the last three years.
3. “Synthesis of Substituted 1,2-Dihydroquinolines and Quinolines from Aromatic Amines and Alkynes by Gold(I)-Catalyzed Tandem Hydroamination-Hydroarylation under Microwave-Assisted Conditions” (X.-Y. Liu, P. Ding, J.-S. Huang, C.-M. Che, Org. Lett., 2007, 9, 26452648) is highlighted on the website http://www.organic-chemistry.org/Highlights/2007/15August.shtm
4. “Highly Efficient and Regioselective Platinum(II)-Catalyzed Tandem Synthesis of Multiply Substituted Indolines and Tetrahydroquinolines” (X.-Y. Liu, C.-M. Che, Angew. Chem. Int. Ed., 2009, 48, 23672371) is selected by the Editorial Board of SYNFACTS and published in SYNFACTS issue 06/09.
5. “Synthesis of Chiral Secondary Amines by Gold(I)-Chiral Bronsted Acid Catalysis” (X.-Y. Liu, C.-M. Che, Org. Lett., 2009, 11, 42044207) is selected by the Editorial Board of SYNFACTS and published in SYNFACTS issue 12/09.

研究方向

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